About Karla

Karla Claudio is curious and passionate about medicine. She completed a Bachelor of Science (B.S.) degree and a Doctor of Philosophy (Ph.D) degree in Pharmacology at University of Puerto Rico with the goal of contributing to the field of biomedical sciences. Her doctoral dissertation was in precision medicine investigating the pharmacogenetics of warfarin. Then, she moved to University of Florida to expand her research experience investigating the genetic basis of psychiatric diseases, specifically, tic disorders. She has presented her research in oral and poster presentations in different national and international scientific conferences and has seven publications in peer-reviewed journals and one book chapter. 

Karla’s main professional goal is to use her scientific knowledge and skills to influence and advance the field of medicine, particularly, precision medicine. 

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Karla Claudio, Ph.D

Postdoctoral Fellow in Genomic Medicine

University of Florida

Working with the Hi-Seq genome sequencer

Cold Spring Harbor Laboratory Sequencing Center, NY

Working at Dr. Jorge Duconge’s Laboratory

University of Puerto Rico, Medical Sciences Campus

        Research Projects

Cytotoxic properties of S. Tulae

Extracts from simarouba tulae as potential cytotoxic agents 

Extracts from Simarouba tulae, an endemic plant of Puerto Rico showed cytotoxic activity in a brine shrimp lethality test.

Principal Investigator: Dr. Claudia Ospina, Professor at University of Puerto Rico 

Pharmacogenetics of warfarin in the admixed Puerto Rican Population

Variants in the genes CYP2C9, VKORC1 and CYP4F2 were found to significantly predict optimal initial warfarin dose. 

Principal Investigator: Dr. Jorge Duconge, Professor at University of Puerto Rico, School of Pharmacy

 

 

Psychiatric Genomics

Genetics and clinical manifestations of tic disorders

The aim of this project is to identify the genetic basis of Tourette’s syndrome and understand the clinical manifestations of this disorder and Persistent Motor or Vocal tics (also known as chronic tics). 

Principal Investigator: Dr. Carol Mathews, Professor at University of Florida, College of Medicine

 

 

                   Blog

 

 

 

Direct-to-consumer (DTC) genetic testing are popular these days but only a few know how do they determine our ancestry and disease risk. On this article, the most common questions about DTC testing are answered. 

 

 

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